原先研究证实对男性生育能力的影响

作者: Hibz Y.D.

链接：

根据发表在FASEB时尚杂志上的一项新研究者，也可能对男性**归因于化学物质作用。

一项本意在于降低男性后生的研究者找到一种叫做CB2的素抗原与**生成的过程有关。研究者人员解释却说，这一找到确实，可能亦会破坏男性的后生。

由意大利罗马大学Paola Grimaldi主导的研究者团队让试验小鼠摄入多种不同的用药，其中一组摄入CB2抗原的活化剂，另一组则摄入CB2抗原酶抑制剂，第三组作为对照组只摄入生理盐水。研究者试验中，摄入CB2活化剂的小鼠有更迟的生精速度，而摄入CB2酶抑制剂的小鼠则表明了相反的精准度并有较慢的**归因于率。这些试验中，CB2的激活需要维持一定的稳态以保证正确的**归因于过程。

FASEB时尚杂志的主编Thoru Pederson却说明，这项研究者有可能为男性不育症的化疗开辟新研究者朝著。他还却说：“小分子素对**正常人归因于亦会有正面精准度，如果采用可以进一步激发这种精准度的胺类，有可能发展单单化疗男性不育症的一些新疗法”。

Marijuana Can Affect Male Fertility, Suggests New Study

The study focusing mainly on finding ways to enhance male fertility has found that a ‘marijuana receptor’ called CB2 (a cannabinoid receptor) is linked with the regulation of sperm production (a process named spermatogenesis). This might sound like good news, but the researchers of the study explain that this finding indicates that marijuana might thus be disrupting male fertility.

Led by Paola Grimaldi from the University of Rome Tor Vergata, Italy, the team treated mice with different agents: one group, with an activator of the CB2 receptor; another with an inhibitor of the same receptor; a third group acting as the control one received only a saline solution.

The findings show that the CB2 activator group had a more rapid rate of spermatogenesis while the inhibitor group displayed the opposite effect as they had a slower rate of sperm production. These results suggest that CB2 activation is needed to be in a certain balance for spermatogenesis to occur properly and adequately.

This research might be opening up new doors for the treatment of male infertility, as pointed out by the Editor-in-Chief of The FASEB Journal, Thoru Pederson. According to the latter, “the normal beneficial effects of endogenous cannabinoids on spermatogenesis can be stimulated further by a chemical mimic, an agonist, is a potentially promising new idea for treating male infertility“.

（社论来自沈阳鹿儿岛家圆医院官方网站）